GUIDE Biology Beginner

Cells and Organelles

Every living thing is made of cells. This guide explains what the main organelles do, how they differ between animal and plant cells, and why their structure fits their function.

Primary sources: Molecular Biology of the Cell (Alberts et al., NCBI) · Nature Scitable — Cell Organelles

01 · What is a cell

The basic unit of life.

All living organisms are made from one or more cells. The cell theory, established by Schleiden, Schwann and Virchow in the 19th century, states three things: all organisms consist of cells; the cell is the basic unit of life; all cells come from pre-existing cells.

Cells fall into two broad groups. Prokaryotic cells — bacteria and archaea — have no membrane-bound nucleus. Their DNA floats in the cytoplasm in a region called the nucleoid. Eukaryotic cells — animals, plants, fungi and protists — have a true nucleus enclosed by a double membrane, and a range of specialised membrane-bound compartments called organelles.

This guide focuses on eukaryotic cells, because they are the ones covered in most secondary-school and first-year university biology courses. For the full comparison, see the NCBI Molecular Biology of the Cell.

02 · The organelles

Ten structures, one cell.

Each organelle has a specific job. The list below covers both animal and plant cells — those marked "Plant only" are not found in animal cells.

Nucleus

Stores DNA and controls gene expression.

Mitochondrion

Produces ATP by aerobic respiration.

Ribosome

Assembles amino acids into proteins.

Endoplasmic reticulum

Rough ER folds proteins; smooth ER makes lipids.

Golgi apparatus

Modifies, packages and ships proteins.

Lysosome

Contains digestive enzymes; breaks down waste.

Cell membrane

Phospholipid bilayer; controls what enters and leaves.

Chloroplast

Plant only — captures light for photosynthesis.

Cell wall

Plant/fungi only — rigid outer layer for support.

Vacuole

Storage; central vacuole in plants maintains turgor pressure.

03 · Animal vs plant cells

Same toolkit, different extras.

Both animal and plant cells share a nucleus, mitochondria, ribosomes, endoplasmic reticulum, Golgi apparatus and a cell membrane. Plant cells have three additional structures:

  • Cell wall — made of cellulose. Provides rigid support and prevents over-expansion.
  • Chloroplasts — contain chlorophyll and carry out photosynthesis. See the photosynthesis guide for details.
  • Large central vacuole — stores water and maintains turgor pressure, keeping the plant upright.

Animal cells have centrioles (used in cell division) and no cell wall; their vacuoles, if present, are small. For cell division details, see the mitosis and meiosis guide.

04 · The nucleus

The cell's control centre.

The nucleus is enclosed by a nuclear envelope — two membranes with nuclear pores that regulate the passage of molecules. Inside, DNA is wrapped around histone proteins to form chromatin. When a cell divides, chromatin condenses into visible chromosomes. Human cells contain 46 chromosomes arranged in 23 pairs. For how DNA is copied and expressed, see the DNA, genes and heredity guide and the protein synthesis guide.

The nucleolus is a dense region inside the nucleus where ribosomal RNA is made. Ribosomes assembled here move to the rough ER where they translate mRNA into protein.

Questions about cells and organelles

Prokaryotic cells (bacteria, archaea) have no membrane-bound nucleus and are generally smaller. Eukaryotic cells (animals, plants, fungi, protists) have a nucleus and membrane-bound organelles. See the Molecular Biology of the Cell overview (NCBI) for a full comparison.

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Follow the biology foundations path: DNA → mitosis → photosynthesis → respiration.

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